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New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study.
Chrobak, Elwira; Kadela-Tomanek, Monika; Bebenek, Ewa; Marciniec, Krzysztof; Wietrzyk, Joanna; Trynda, Justyna; Pawelczak, Bartosz; Kusz, Joachim; Kasperczyk, Janusz; Chodurek, Ewa; Paduszynski, Piotr; Boryczka, Stanislaw.
Afiliación
  • Chrobak E; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Organic Chemistry, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland. Electronic address: echrobak@sum.edu.pl.
  • Kadela-Tomanek M; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Organic Chemistry, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland.
  • Bebenek E; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Organic Chemistry, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland.
  • Marciniec K; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Organic Chemistry, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland.
  • Wietrzyk J; Polish Academy of Sciences, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Department of Experimental Oncology, 12 R.Weigla Str., 53-114 Wroclaw, Poland.
  • Trynda J; Polish Academy of Sciences, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Department of Experimental Oncology, 12 R.Weigla Str., 53-114 Wroclaw, Poland.
  • Pawelczak B; Rainbow Pharmacy, 25 Jana Matejki Str., 43-600 Jaworzno, Poland.
  • Kusz J; University of Silesia, Institute of Physics, 1 75Pulku Piechoty Str., 41 500 Chorzów, Poland.
  • Kasperczyk J; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Biopharmacy, 8 Jednosci Str., 41-200 Sosnowiec, Poland; Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 Curie-Sklodowska Str., 41-819 Zabrze, Pola
  • Chodurek E; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Biopharmacy, 8 Jednosci Str., 41-200 Sosnowiec, Poland.
  • Paduszynski P; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Biopharmacy, 8 Jednosci Str., 41-200 Sosnowiec, Poland.
  • Boryczka S; Medical University of Silesia in Katowice, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Department of Organic Chemistry, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland.
Bioorg Chem ; 87: 613-628, 2019 06.
Article en En | MEDLINE | ID: mdl-30947097

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfatos / Triterpenos / Simulación del Acoplamiento Molecular / Antineoplásicos Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfatos / Triterpenos / Simulación del Acoplamiento Molecular / Antineoplásicos Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article