Exosome-shuttled miR-92b-3p from ischemic preconditioned astrocytes protects neurons against oxygen and glucose deprivation.

Xu, Lili; Cao, Hui; Xie, Yi; Zhang, Yao; Du, Mingyang; Xu, Xiaohui; Ye, Ruidong; Liu, Xinfeng

Xu, Lili; Cao, Hui; Xie, Yi; Zhang, Yao; Du, Mingyang; Xu, Xiaohui; Ye, Ruidong; Liu, Xinfeng.

Afiliación

Xu L; Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China; Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
Cao H; Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
Xie Y; Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zhang Y; Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
Du M; Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
Xu X; Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
Ye R; Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. Electronic address: yeruid@gmail.com.
Liu X; Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. Electronic address: xfliu2@vip.163.com.

Brain Res ; 1717: 66-73, 2019 08 15.

Article en En | MEDLINE | ID: mdl-30986407

Asunto(s)

Astrocitos/metabolismo; Isquemia Encefálica/genética; MicroARNs/metabolismo; Animales; Apoptosis/efectos de los fármacos; Isquemia Encefálica/metabolismo; Hipoxia de la Célula/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Embrión de Mamíferos; Exoma/fisiología; Femenino; Glucosa/metabolismo; Precondicionamiento Isquémico/métodos; Masculino; MicroARNs/genética; Neuronas/metabolismo; Neuroprotección/efectos de los fármacos; Fármacos Neuroprotectores/farmacología; Oxígeno/metabolismo; Ratas; Ratas Sprague-Dawley; Transducción de Señal/efectos de los fármacos

Palabras clave

Astrocyte; Exosome; Ischemic preconditioning; MicroRNA-92b-3p; Oxygen and glucose deprivation

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Isquemia Encefálica / Astrocitos / MicroARNs Idioma: En Revista: Brain Res Año: 2019 Tipo del documento: Article

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