Significant changes in hepatic transcriptome and circulating miRNAs are associated with diet-induced metabolic syndrome in apoE3L.CETP mice.

Nasias, Dimitris; Evangelakos, Ioannis; Nidris, Vasilis; Vassou, Despoina; Tarasco, Erika; Lutz, Thomas A; Kardassis, Dimitris

Nasias, Dimitris; Evangelakos, Ioannis; Nidris, Vasilis; Vassou, Despoina; Tarasco, Erika; Lutz, Thomas A; Kardassis, Dimitris.

Afiliación

Nasias D; Laboratory of Biochemistry, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece.
Evangelakos I; Gene Regulation and Epigenetics group, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion, Greece.
Nidris V; Laboratory of Biochemistry, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece.
Vassou D; Gene Regulation and Epigenetics group, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion, Greece.
Tarasco E; Laboratory of Biochemistry, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece.
Lutz TA; Gene Regulation and Epigenetics group, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion, Greece.
Kardassis D; Genomics Facility, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion, Greece.

J Cell Physiol ; 234(11): 20485-20500, 2019 11.

Article en En | MEDLINE | ID: mdl-31016757

Asunto(s)

Dieta Alta en Grasa; Hígado/metabolismo; Síndrome Metabólico/genética; Síndrome Metabólico/metabolismo; Animales; MicroARN Circulante/genética; Dieta con Restricción de Grasas/efectos adversos; Dieta Alta en Grasa/efectos adversos; Grasas de la Dieta/metabolismo; Modelos Animales de Enfermedad; Hígado Graso/metabolismo; Perfilación de la Expresión Génica/métodos; Masculino; Ratones; Obesidad/metabolismo

Palabras clave

MetS; apoE3L.CETP mice; gene signatures; metabolic syndrome; microarrays; transcriptomics

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome Metabólico / Dieta Alta en Grasa / Hígado Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Cell Physiol Año: 2019 Tipo del documento: Article

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