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Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia.
Wiggers, Caroline R M; Govers, Anita M A P; Lelieveld, Daphne; Egan, David A; Zwaan, C Michel; Sonneveld, Edwin; Coffer, Paul J; Bartels, Marije.
Afiliación
  • Wiggers CRM; Department of Pediatric Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Govers AMAP; Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Lelieveld D; Department of Pediatric Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Egan DA; Center for Molecular Medicine and Regenerative Medicine Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Zwaan CM; Cell Screening Core, Department of Cell Biology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Sonneveld E; Cell Screening Core, Department of Cell Biology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Coffer PJ; Prinsess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Bartels M; Department of Pediatric Hematology and Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Pediatr Blood Cancer ; 66(8): e27785, 2019 08.
Article en En | MEDLINE | ID: mdl-31044544
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Leucemia Mieloide Aguda / Epigénesis Genética / Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Hidroxiquinolinas / Compuestos Nitrosos Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Pediatr Blood Cancer Asunto de la revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Año: 2019 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Leucemia Mieloide Aguda / Epigénesis Genética / Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Hidroxiquinolinas / Compuestos Nitrosos Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Pediatr Blood Cancer Asunto de la revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Año: 2019 Tipo del documento: Article