Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.

Ferent, Julien; Giguère, Fanny; Jolicoeur, Christine; Morin, Steves; Michaud, Jean-Francois; Makihara, Shirin; Yam, Patricia T; Cayouette, Michel; Charron, Frederic

Ferent, Julien; Giguère, Fanny; Jolicoeur, Christine; Morin, Steves; Michaud, Jean-Francois; Makihara, Shirin; Yam, Patricia T; Cayouette, Michel; Charron, Frederic.

Afiliación

Ferent J; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Department of Neuroscience, University of Montreal, Montreal, QC H3T 1J4, Canada.
Giguère F; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Jolicoeur C; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Morin S; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Michaud JF; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Makihara S; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Yam PT; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Cayouette M; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Department of Anatomy and Cell Biology, Division of Experimental Medicine, McGill University, Montreal, QC H3A 0G4, Canada; Department of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada.
Charron F; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Department of Anatomy and Cell Biology, Division of Experimental Medicine, McGill University, Montreal, QC H3A 0G4, Canada; Department of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada; D

Neuron ; 102(6): 1157-1171.e5, 2019 06 19.

Article en En | MEDLINE | ID: mdl-31054872

Asunto(s)

Orientación del Axón/genética; Endocitosis/genética; Conos de Crecimiento/metabolismo; Proteínas Hedgehog/metabolismo; Inmunoglobulina G/metabolismo; Proteínas de la Membrana/genética; Proteínas del Tejido Nervioso/genética; Neuronas/metabolismo; Receptor Patched-1/metabolismo; Receptores de Superficie Celular/metabolismo; Animales; Técnicas de Silenciamiento del Gen; Proteínas de la Membrana/metabolismo; Ratones; Proteínas del Tejido Nervioso/metabolismo

Palabras clave

Boc; Numb; Patched1; axon guidance; commissural neurons; endocytosis; sonic hedgehog

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Receptores de Superficie Celular / Conos de Crecimiento / Endocitosis / Proteínas Hedgehog / Receptor Patched-1 / Orientación del Axón / Proteínas de la Membrana / Proteínas del Tejido Nervioso / Neuronas Tipo de estudio: Guideline Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article

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