Rescue of Infectious Recombinant Hazara Nairovirus from cDNA Reveals the Nucleocapsid Protein DQVD Caspase Cleavage Motif Performs an Essential Role other than Cleavage.

Fuller, J; Surtees, R A; Slack, G S; Mankouri, J; Hewson, R; Barr, J N

Fuller, J; Surtees, R A; Slack, G S; Mankouri, J; Hewson, R; Barr, J N.

Afiliación

Fuller J; School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Surtees RA; School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Slack GS; National Infection Service, Public Health England, Salisbury, United Kingdom.
Mankouri J; School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Hewson R; National Infection Service, Public Health England, Salisbury, United Kingdom.
Barr JN; School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom j.n.barr@leeds.ac.uk.

J Virol ; 93(15)2019 08 01.

Article en En | MEDLINE | ID: mdl-31118258

Asunto(s)

Caspasas/metabolismo; Interacciones Huésped-Patógeno; Nairovirus/fisiología; Proteínas de la Nucleocápside/metabolismo; Replicación Viral; Animales; Línea Celular; ADN Complementario/genética; ADN Viral/genética; Humanos; Genética Inversa

Palabras clave

Hazara virus; caspases; reverse genetics; virus rescue

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Replicación Viral / Nairovirus / Proteínas de la Nucleocápside / Caspasas / Interacciones Huésped-Patógeno Idioma: En Revista: J Virol Año: 2019 Tipo del documento: Article

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