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NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition.
De Paula, Viviane S; Sgourakis, Nikolaos G; Francischetti, Ivo M B; Almeida, Fabio C L; Monteiro, Robson Q; Valente, Ana Paula.
Afiliación
  • De Paula VS; Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA.
  • Sgourakis NG; Centro de Biologia Estrutural e Bioimagem, Rio de Janeiro, Brazil.
  • Francischetti IMB; Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA.
  • Almeida FCL; Vector Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
  • Monteiro RQ; Centro de Biologia Estrutural e Bioimagem, Rio de Janeiro, Brazil.
  • Valente AP; Instituto de Bioquímica Médica, Centro Nacional de Ressonância Magnética Nuclear Jiri Jonas, Universidade Federal do Rio de Janeiro, Brazil; and.
Blood ; 134(8): 699-708, 2019 08 22.
Article en En | MEDLINE | ID: mdl-31133602
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas y Péptidos Salivales / Factor Xa / Inhibidores del Factor Xa Tipo de estudio: Prognostic_studies Idioma: En Revista: Blood Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas y Péptidos Salivales / Factor Xa / Inhibidores del Factor Xa Tipo de estudio: Prognostic_studies Idioma: En Revista: Blood Año: 2019 Tipo del documento: Article