Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.

Lu, Hong; Cheng, Shuibing; Wu, Cunzao; Zheng, Shizhang; Hong, Weilong; Liu, Leping; Bai, Yongheng

Lu, Hong; Cheng, Shuibing; Wu, Cunzao; Zheng, Shizhang; Hong, Weilong; Liu, Leping; Bai, Yongheng.

Afiliación

Lu H; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China; Department of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Chi
Cheng S; Department of Trauma Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wu C; Department of Transplantation, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Zheng S; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Hong W; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Liu L; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Bai Y; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Electronic address: wzbyh@wmu.edu.cn.

Phytomedicine ; 62: 152976, 2019 Sep.

Article en En | MEDLINE | ID: mdl-31177020

Asunto(s)

Inflamación/tratamiento farmacológico; Extractos Vegetales/farmacología; Sedum/química; Animales; Riñón/inmunología; Riñón/lesiones; Lipopolisacáridos/farmacología; Activación de Macrófagos/efectos de los fármacos; Macrófagos/efectos de los fármacos; Macrófagos/inmunología; Masculino; Óxido Nítrico Sintasa de Tipo II/efectos de los fármacos; Óxido Nítrico Sintasa de Tipo II/metabolismo; Extractos Vegetales/química; Ratas; Ratas Sprague-Dawley; Factor de Transcripción ReIA/efectos de los fármacos; Factor de Transcripción ReIA/metabolismo

Palabras clave

IRF5; Inflammatory macrophage polarization; Kidney injury; NF-κB p65; Sedum sarmentosum Bunge

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Sedum / Inflamación Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2019 Tipo del documento: Article

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