Disorders of Ventral Induction/Spectrum of Holoprosencephaly.
Neuroimaging Clin N Am
; 29(3): 411-421, 2019 Aug.
Article
en En
| MEDLINE
| ID: mdl-31256862
ABSTRACT
Disorders of the ventral induction give rise to a group of congenital malformations that share in common the failure of the prosencephalon cleavage and subsequent formation of midline structures, presenting with a wide spectrum of severity. This article focuses on the imaging findings of the holoprosencephaly spectrum and septo-optic dysplasia, their epidemiology, embryology, and the common clinical associated anomalies. Knowledge of the imaging features of these disorders is necessary for a correct interpretation of findings and accurate parental counseling. Diagnostic evaluation of patients should include molecular screening and genetic counseling to characterize prognosis and risk of recurrence.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Imagen por Resonancia Magnética
/
Holoprosencefalia
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Neuroimaging Clin N Am
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
NEUROLOGIA
Año:
2019
Tipo del documento:
Article