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Canine histiocytic sarcoma cell lines with SHP2 p.Glu76Gln or p.Glu76Ala mutations are sensitive to allosteric SHP2 inhibitor SHP099.
Tani, Hiroyuki; Kurita, Sena; Miyamoto, Ryo; Ochiai, Kazuhiko; Tamura, Kyoichi; Bonkobara, Makoto.
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  • Tani H; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
  • Kurita S; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
  • Miyamoto R; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
  • Ochiai K; Department of Basic Science, School of Veterinary Nursing and Technology Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
  • Tamura K; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
  • Bonkobara M; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.
Vet Comp Oncol ; 18(2): 161-168, 2020 Jun.
Article en En | MEDLINE | ID: mdl-31339650
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperidinas / Pirimidinas / Regulación Neoplásica de la Expresión Génica / Sarcoma Histiocítico / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Antineoplásicos Tipo de estudio: Diagnostic_studies Idioma: En Revista: Vet Comp Oncol Asunto de la revista: MEDICINA VETERINARIA / NEOPLASIAS Año: 2020 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperidinas / Pirimidinas / Regulación Neoplásica de la Expresión Génica / Sarcoma Histiocítico / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Antineoplásicos Tipo de estudio: Diagnostic_studies Idioma: En Revista: Vet Comp Oncol Asunto de la revista: MEDICINA VETERINARIA / NEOPLASIAS Año: 2020 Tipo del documento: Article