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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).
Reid, Emily E; Archer, Katie E; Shizuka, Manami; McShea, Molly A; Maloney, Erin K; Ab, Olga; Lanieri, Leanne; Wilhelm, Alan; Ponte, Jose F; Yoder, Nicholas C; Chari, Ravi V J; Miller, Michael L.
Afiliación
  • Reid EE; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Archer KE; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Shizuka M; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • McShea MA; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Maloney EK; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Ab O; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Lanieri L; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Wilhelm A; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Ponte JF; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Yoder NC; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Chari RVJ; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States.
  • Miller ML; ImmunoGen, Inc., 830 Winter Street, Waltham, MA 02451, United States. Electronic address: michael.miller@immunogen.com.
Bioorg Med Chem Lett ; 29(17): 2455-2458, 2019 09 01.
Article en En | MEDLINE | ID: mdl-31350125

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inmunoconjugados / Alquilantes Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inmunoconjugados / Alquilantes Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article