Conserved residue His-257 of <i>Vibrio cholerae</i> flavin transferase ApbE plays a critical role in substrate binding and catalysis.

Fang, Xuan; Osipiuk, Jerzy; Chakravarthy, Srinivas; Yuan, Ming; Menzer, William M; Nissen, Devin; Liang, Pingdong; Raba, Daniel A; Tuz, Karina; Howard, Andrew J; Joachimiak, Andrzej; Minh, David D L; Juarez, Oscar

Conserved residue His-257 of Vibrio cholerae flavin transferase ApbE plays a critical role in substrate binding and catalysis.

Fang, Xuan; Osipiuk, Jerzy; Chakravarthy, Srinivas; Yuan, Ming; Menzer, William M; Nissen, Devin; Liang, Pingdong; Raba, Daniel A; Tuz, Karina; Howard, Andrew J; Joachimiak, Andrzej; Minh, David D L; Juarez, Oscar.

Afiliación

Fang X; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Osipiuk J; Center for Structural Genomics of Infectious Diseases (CSGID), Consortium for Advanced Science and Engineering, University of Chicago, Chicago, Illinois 60637.
Chakravarthy S; Structural Biology Center, Biosciences Division, Argonne National Laboratory, Lemont, Illinois 60439.
Yuan M; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Menzer WM; Biophysics Collaborative Access Team, Advanced Photon Source, Argonne National Laboratory, Lemont, Illinois 60439.
Nissen D; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Liang P; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Raba DA; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Tuz K; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Howard AJ; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Joachimiak A; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Minh DDL; Department of Biological Sciences, Illinois Institute of Technology, Chicago, Illinois 60616.
Juarez O; Center for Structural Genomics of Infectious Diseases (CSGID), Consortium for Advanced Science and Engineering, University of Chicago, Chicago, Illinois 60637.

J Biol Chem ; 294(37): 13800-13810, 2019 09 13.

Article en En | MEDLINE | ID: mdl-31350338

Asunto(s)

Flavinas/metabolismo; Transferasas/metabolismo; Vibrio cholerae/metabolismo; Proteínas Bacterianas/metabolismo; Catálisis; Dominio Catalítico; Secuencia Conservada; Mononucleótido de Flavina/metabolismo; Flavina-Adenina Dinucleótido/metabolismo; Flavinas/genética; Histidina/metabolismo; Cinética; Oxidación-Reducción; Especificidad por Sustrato/genética; Transferasas/genética; Vibrio cholerae/genética

Palabras clave

Acid base catalysis; ApbE; NQR; Vibrio cholerae; electron transfer; enzyme catalysis; enzyme mechanism; flavin adenine dinucleotide (FAD); flavin mononucleotide (FMN); flavin transferase; flavoprotein; protein assembly

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transferasas / Vibrio cholerae / Flavinas Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transferasas / Vibrio cholerae / Flavinas Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article