Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models.

Lee, Mijeong; Kim, Yeon-Soo; Lee, Kyoungmin; Kang, Moonkyung; Shin, Hyemi; Oh, Jeong-Woo; Koo, Harim; Kim, Donggeon; Kim, Yejin; Kong, Doo-Sik; Nam, Do-Hyun; Lee, Hye Won

Lee, Mijeong; Kim, Yeon-Soo; Lee, Kyoungmin; Kang, Moonkyung; Shin, Hyemi; Oh, Jeong-Woo; Koo, Harim; Kim, Donggeon; Kim, Yejin; Kong, Doo-Sik; Nam, Do-Hyun; Lee, Hye Won.

Afiliación

Lee M; Department of Health Science & Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea.
Kim YS; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea.
Lee K; Graduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 34134, Korea.
Kang M; Department of Health Science & Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea.
Shin H; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea.
Oh JW; Graduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 34134, Korea.
Koo H; Department of Health Science & Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea.
Kim D; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea.
Kim Y; Department of Health Science & Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea.
Kong DS; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea.
Nam DH; Department of Health Science & Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea.
Lee HW; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea.

Cancers (Basel) ; 11(8)2019 Jul 31.

Article en En | MEDLINE | ID: mdl-31370279

Palabras clave

bystander effect; dual suicide gene therapy; glioblastoma; patient-derived glioblastoma stem-like cells; semi- and pseudotyped-retroviral replicating vector

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