Optical/MRI dual-modality imaging of M1 macrophage polarization in atherosclerotic plaque with MARCO-targeted upconversion luminescence probe.

Wang, Yabin; Zhang, Yan; Wang, Zhao; Zhang, Jibin; Qiao, Rui Rui; Xu, Mengqi; Yang, Ning; Gao, Lei; Qiao, Hongyu; Gao, Mingyuan; Cao, Feng

Optical/MRI dual-modality imaging of M1 macrophage polarization in atherosclerotic plaque with MARCO-targeted upconversion luminescence probe.

Wang, Yabin; Zhang, Yan; Wang, Zhao; Zhang, Jibin; Qiao, Rui Rui; Xu, Mengqi; Yang, Ning; Gao, Lei; Qiao, Hongyu; Gao, Mingyuan; Cao, Feng.

Afiliación

Wang Y; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China; Department of Cardiology, Chinese Eastern Theatre Naval Hospital, Zhejiang, 316000, China.
Zhang Y; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China; TEDA International Cardiovascular Hospital, Tianjin, 300457, China.
Wang Z; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Zhang J; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Qiao RR; Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, Beijing, 100190, China.
Xu M; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Yang N; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Gao L; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Qiao H; Department of Pediatric, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Gao M; Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, Beijing, 100190, China. Electronic address: gaomy@iccas.ac.cn.
Cao F; Department of Cardiology & National Clinical Research Center of Geriatric Disease, 2nd Medical Center of Chinese PLA General Hospital, Beijing, 100853, China. Electronic address: fengcao8828@163.com.

Biomaterials ; 219: 119378, 2019 10.

Article en En | MEDLINE | ID: mdl-31382209

Asunto(s)

Polaridad Celular; Luminiscencia; Macrófagos/patología; Imagen por Resonancia Magnética; Imagen Multimodal; Imagen Óptica; Placa Aterosclerótica/diagnóstico por imagen; Receptores Inmunológicos/metabolismo; Animales; Muerte Celular; Estenosis Coronaria/sangre; Citocinas/sangre; Femenino; Humanos; Mediadores de Inflamación/sangre; Lipoproteínas LDL/farmacología; Modelos Logísticos; Masculino; Ratones Endogámicos C57BL; Persona de Mediana Edad; Nanopartículas/química; Nanopartículas/ultraestructura; Fenotipo; Placa Aterosclerótica/sangre; Placa Aterosclerótica/patología; Índice de Severidad de la Enfermedad

Palabras clave

M1 macrophage polarization; Multimodality molecular imaging; Upconversion nanoprobe; Vulnerable atherosclerotic plaque

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Receptores Inmunológicos / Polaridad Celular / Luminiscencia / Placa Aterosclerótica / Imagen Multimodal / Imagen Óptica / Macrófagos Tipo de estudio: Risk_factors_studies Idioma: En Revista: Biomaterials Año: 2019 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google