Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk.

Harris, Kelly L; Myers, Meagan B; McKim, Karen L; Elespuru, Rosalie K; Parsons, Barbara L

Harris, Kelly L; Myers, Meagan B; McKim, Karen L; Elespuru, Rosalie K; Parsons, Barbara L.

Afiliación

Harris KL; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas.
Myers MB; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas.
McKim KL; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas.
Elespuru RK; Division of Biology, Chemistry and Materials Science, CDRH/OSEL, US Food and Drug Administration, Silver Spring, Maryland.
Parsons BL; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas.

Environ Mol Mutagen ; 61(1): 152-175, 2020 01.

Article en En | MEDLINE | ID: mdl-31469467

Asunto(s)

Carcinogénesis/genética; Mutación; Neoplasias/genética; Animales; Biomarcadores de Tumor/genética; Carcinogénesis/inducido químicamente; Carcinógenos/toxicidad; Secuenciación de Nucleótidos de Alto Rendimiento/métodos; Humanos; Mutación/efectos de los fármacos; Neoplasias/inducido químicamente; Medición de Riesgo/métodos

Palabras clave

biomarker; cancer risk assessment; carcinogenesis; cell communication; cell signaling; mutation

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinogénesis / Mutación / Neoplasias Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: Environ Mol Mutagen Asunto de la revista: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Año: 2020 Tipo del documento: Article

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