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Selenosulfides Tethered to gem-Dimethyl Esters: A Robust and Highly Versatile Framework for H2 S Probe Development.
Suarez, S Israel; Ambrose, Rynne; Kalk, Madison A; Lukesh, John C.
Afiliación
  • Suarez SI; Department of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, NC, 27101, USA.
  • Ambrose R; Department of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, NC, 27101, USA.
  • Kalk MA; Department of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, NC, 27101, USA.
  • Lukesh JC; Department of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, NC, 27101, USA.
Chemistry ; 25(69): 15736-15740, 2019 Dec 10.
Article en En | MEDLINE | ID: mdl-31576582
ABSTRACT
Selenosulfides coupled to gem-dimethyl esters provide an exceptional platform for H2 S probe development. With the sulfur half being nonessential to its high reactivity and selectivity towards H2 S, we highlight the unique flexibility of our design by improving its biocompatibility and tissue specificity through structural modifications of its sulfide moiety.
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article