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Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.
Gooding, Sarah; Olechnowicz, Sam W Z; Morris, Emma V; Armitage, Andrew E; Arezes, Joao; Frost, Joe; Repapi, Emmanouela; Edwards, James R; Ashley, Neil; Waugh, Craig; Gray, Nicola; Martinez-Hackert, Erik; Lim, Pei Jin; Pasricha, Sant-Rayn; Knowles, Helen; Mead, Adam J; Ramasamy, Karthik; Drakesmith, Hal; Edwards, Claire M.
Afiliación
  • Gooding S; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Olechnowicz SWZ; Oxford University Hospitals NHS Trust, Oxford, UK.
  • Morris EV; NIHR Oxford Biomedical Research Centre Blood Theme, University of Oxford, Oxford, UK.
  • Armitage AE; Oxford Centre for Translational Myeloma Research, University of Oxford, Oxford, UK.
  • Arezes J; Oxford Centre for Translational Myeloma Research, University of Oxford, Oxford, UK.
  • Frost J; Nuffield Dept. of Surgical Sciences, University of Oxford, Oxford, UK.
  • Repapi E; Oxford Centre for Translational Myeloma Research, University of Oxford, Oxford, UK.
  • Edwards JR; Nuffield Dept. of Surgical Sciences, University of Oxford, Oxford, UK.
  • Ashley N; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Waugh C; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Gray N; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Martinez-Hackert E; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Lim PJ; Oxford Centre for Translational Myeloma Research, University of Oxford, Oxford, UK.
  • Pasricha SR; Nuffield Dept. of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK.
  • Knowles H; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Mead AJ; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Ramasamy K; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Drakesmith H; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
  • Edwards CM; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Nat Commun ; 10(1): 4533, 2019 10 04.
Article en En | MEDLINE | ID: mdl-31586071
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Células Madre / Enfermedades Óseas / Proteínas Morfogenéticas Óseas / Mieloma Múltiple Tipo de estudio: Etiology_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Células Madre / Enfermedades Óseas / Proteínas Morfogenéticas Óseas / Mieloma Múltiple Tipo de estudio: Etiology_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article