Chemical investigation on the root bark of Bombax malabarica.
Fitoterapia
; 139: 104376, 2019 Nov.
Article
en En
| MEDLINE
| ID: mdl-31629048
ABSTRACT
Ten compounds were isolated from the root bark of Bombax malabarica, including two new compounds, bombamalin (1) and 3,4,5-trimethoxyphenol-1-[ß-xylopyranosyl-(1â¯ââ¯2)]-ß-glucopyranoside (3), and shorealactone (4), a rare dehydroascorbic acid fused l-ε-viniferin. Compound 1 is an unusual bissesquiterpene, containing a 1,4-dioxene ring formed by fusing isohemigossypol with ent-cadinen-2-one. Their structures were elucidated by extensive spectroscopic analysis. This chemical reinvestigation is of value for chemotaxonomy of the Bombax genus, in particular the finding of the unusual 1 and rare 4. Among the isolates, shorealactone (4), l-epicatechin 5-O-ß-D-xyloside (5), and 2-C-[ß-D-apiosyl-(1â¯ââ¯6)]- ß-D-glucosyl]-1,3,6-trihydroxy-7-methoxyxanthone (6) displayed some inhibition against α-glucosidase with IC50 values of 224, 345, and 285⯵M, respectively.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Raíces de Plantas
/
Corteza de la Planta
/
Bombax
/
Fitoquímicos
País/Región como asunto:
Asia
Idioma:
En
Revista:
Fitoterapia
Año:
2019
Tipo del documento:
Article