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HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway.
Chen, Jianxu; Chen, Jiandi; Huang, Jiaxin; Li, Zhanyu; Gong, Yihang; Zou, Baojia; Liu, Xialei; Ding, Lei; Li, Peiping; Zhu, Zhiquan; Zhang, Baimeng; Guo, Hui; Cai, Chaonong; Li, Jian.
Afiliación
  • Chen J; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Chen J; Department of Endocrinology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Huang J; Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
  • Li Z; Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Gong Y; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Zou B; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Liu X; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Ding L; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Li P; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Zhu Z; Department of Thoracic Oncology, The Cancer Center of The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Zhang B; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Guo H; Department of Interventional Radiology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Cai C; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
  • Li J; Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Aging (Albany NY) ; 11(23): 10839-10860, 2019 12 04.
Article en En | MEDLINE | ID: mdl-31796646
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Enfermedad del Hígado Graso no Alcohólico / Lípidos / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Enfermedad del Hígado Graso no Alcohólico / Lípidos / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2019 Tipo del documento: Article