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Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Aß aggregation and reducing oligomers formation.
Zhang, Shujuan; Zhang, Jianxiang; Wei, Dongfeng; An, Haiting; Liu, Wei; Lai, Yihui; Yang, Te; Shao, Wen; Huang, Yaping; Wang, Lei; Dou, Fei; Peng, Dantao; Zhang, Zhanjun.
Afiliación
  • Zhang S; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China; Department of Neurology, China-Japan Friendship Hospital, 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China.
  • Zhang J; Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, 100875 Beijing, China.
  • Wei D; BABRI Centre, Beijing Normal University, Beijing 100875, China; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
  • An H; State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China; BABRI Centre, Beijing Normal University, Beijing 100875, China.
  • Liu W; College of Chemistry, Beijing Normal University, Beijing, China.
  • Lai Y; Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, 100875 Beijing, China.
  • Yang T; Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, 100875 Beijing, China.
  • Shao W; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China; Department of Neurology, China-Japan Friendship Hospital, 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China.
  • Huang Y; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China; Department of Neurology, China-Japan Friendship Hospital, 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China.
  • Wang L; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China; Department of Neurology, China-Japan Friendship Hospital, 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China.
  • Dou F; Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, 100875 Beijing, China.
  • Peng D; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China; Department of Neurology, China-Japan Friendship Hospital, 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China. Electronic address: pengdantao2000@163.com.
  • Zhang Z; State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China; BABRI Centre, Beijing Normal University, Beijing 100875, China. Electronic address: zhang_rzs@bnu.edu.cn.
Biomed Pharmacother ; 121: 109682, 2020 Jan.
Article en En | MEDLINE | ID: mdl-31810113
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Péptidos beta-Amiloides / Apigenina / Presenilina-1 / Multimerización de Proteína / Disfunción Cognitiva / Agregado de Proteínas / Glucuronatos Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomed Pharmacother Año: 2020 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Péptidos beta-Amiloides / Apigenina / Presenilina-1 / Multimerización de Proteína / Disfunción Cognitiva / Agregado de Proteínas / Glucuronatos Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomed Pharmacother Año: 2020 Tipo del documento: Article