Optimization of chromatography to overcome matrix effect for reliable estimation of four small molecular drugs from biological fluids using LC-MS/MS.

Trivedi, Vikas; Shah, Priyanka A; Shrivastav, Pranav S; Sanyal, Mallika

Trivedi, Vikas; Shah, Priyanka A; Shrivastav, Pranav S; Sanyal, Mallika.

Afiliación

Trivedi V; Chemistry Department, Kadi Sarva Vishwavidyalaya, Gandhinagar, India.
Shah PA; Department of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, India.
Shrivastav PS; Department of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, India.
Sanyal M; Chemistry Department, St. Xavier's College, Navrangpura, Ahmedabad, India.

Biomed Chromatogr ; 34(3): e4777, 2020 Mar.

Article en En | MEDLINE | ID: mdl-31826316

Asunto(s)

Cromatografía Liquida/métodos; Preparaciones Farmacéuticas/sangre; Espectrometría de Masas en Tándem/métodos; Gemfibrozilo/sangre; Gemfibrozilo/química; Gemfibrozilo/farmacocinética; Humanos; Modelos Lineales; Modelos Químicos; Preparaciones Farmacéuticas/química; Reproducibilidad de los Resultados; Sensibilidad y Especificidad

Palabras clave

LC-ESI-MS/MS; bioanalysis; ion-suppression; pharmacokinetics; small molecular drugs

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Cromatografía Liquida / Espectrometría de Masas en Tándem Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Biomed Chromatogr Año: 2020 Tipo del documento: Article

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