GJA8 missense mutation disrupts hemichannels and induces cell apoptosis in human lens epithelial cells.

Li, Li; Fan, Da-Bei; Zhao, Ya-Ting; Li, Yun; Yang, Zi-Bing; Zheng, Guang-Ying

Li, Li; Fan, Da-Bei; Zhao, Ya-Ting; Li, Yun; Yang, Zi-Bing; Zheng, Guang-Ying.

Afiliación

Li L; Ophthalmologic Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Fan DB; Endocrine Department, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zhao YT; Ophthalmologic Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Li Y; Ophthalmologic Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yang ZB; Ophthalmologic Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zheng GY; Ophthalmologic Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. zzzgy01@126.com.

Sci Rep ; 9(1): 19157, 2019 12 16.

Article en En | MEDLINE | ID: mdl-31844091

Asunto(s)

Apoptosis; Conexinas/genética; Células Epiteliales/metabolismo; Células Epiteliales/patología; Cristalino/patología; Mutación Missense/genética; Secuencia de Bases; Catarata/genética; Femenino; Proteínas Fluorescentes Verdes/metabolismo; Humanos; Masculino; Proteínas Mutantes/metabolismo; NADP/biosíntesis; Linaje; Agregado de Proteínas; Especies Reactivas de Oxígeno/metabolismo; Respuesta de Proteína Desplegada/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Apoptosis / Conexinas / Mutación Missense / Células Epiteliales / Cristalino Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google