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A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Jacob, Fadi; Salinas, Ryan D; Zhang, Daniel Y; Nguyen, Phuong T T; Schnoll, Jordan G; Wong, Samuel Zheng Hao; Thokala, Radhika; Sheikh, Saad; Saxena, Deeksha; Prokop, Stefan; Liu, Di-Ao; Qian, Xuyu; Petrov, Dmitriy; Lucas, Timothy; Chen, H Isaac; Dorsey, Jay F; Christian, Kimberly M; Binder, Zev A; Nasrallah, MacLean; Brem, Steven; O'Rourke, Donald M; Ming, Guo-Li; Song, Hongjun.
Afiliación
  • Jacob F; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Medical Scientist Training Program, Johns Hopkins Univ
  • Salinas RD; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Zhang DY; Biochemistry and Molecular Biophysics Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Nguyen PTT; Neuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Schnoll JG; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Wong SZH; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Thokala R; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sheikh S; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Saxena D; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Prokop S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Liu DA; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Qian X; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Bioengineering Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Petrov D; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lucas T; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Chen HI; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.
  • Dorsey JF; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Christian KM; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Binder ZA; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Nasrallah M; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Brem S; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • O'Rourke DM; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: donald.orourke@pennmedicine.upenn.edu.
  • Ming GL; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, University of Pennsylvania, Philade
  • Song H; Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center, Univ
Cell ; 180(1): 188-204.e22, 2020 01 09.
Article en En | MEDLINE | ID: mdl-31883794
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Organoides / Glioblastoma / Técnicas de Cultivo de Célula Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Organoides / Glioblastoma / Técnicas de Cultivo de Célula Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article