Extracellular mitochondrial DNA promote NLRP3 inflammasome activation and induce acute lung injury through TLR9 and NF-&#954;B.

Extracellular mitochondrial DNA promote NLRP3 inflammasome activation and induce acute lung injury through TLR9 and NF-κB.

Wu, Guannan; Zhu, Qingqing; Zeng, Junli; Gu, Xiaoling; Miao, Yingying; Xu, Wujian; Lv, Tangfeng; Song, Yong.

Afiliación

Wu G; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Zhu Q; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Zeng J; Department of Respiratory Medicine, Jinling Hospital, Southern Medical University (Guangzhou), Nanjing 210002, China.
Gu X; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Miao Y; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Xu W; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Lv T; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.
Song Y; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.

J Thorac Dis ; 11(11): 4816-4828, 2019 Nov.

Article en En | MEDLINE | ID: mdl-31903272