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Effects of spironolactone on serum markers of fibrosis in people at high risk of developing heart failure: rationale, design and baseline characteristics of a proof-of-concept, randomised, precision-medicine, prevention trial. The Heart OMics in AGing (HOMAGE) trial.
Pellicori, Pierpaolo; Ferreira, João Pedro; Mariottoni, Beatrice; Brunner-La Rocca, Hans-Peter; Ahmed, Fozia Z; Verdonschot, Job; Collier, Tim; Cuthbert, Joe J; Petutschnigg, Johannes; Mujaj, Blerim; Girerd, Nicolas; González, Arantxa; Clark, Andrew L; Cosmi, Franco; Staessen, Jan A; Heymans, Stephane; Latini, Roberto; Rossignol, Patrick; Zannad, Faiez; Cleland, John G F.
Afiliación
  • Pellicori P; Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow, UK.
  • Ferreira JP; Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique, INSERM 1433, CHRU de Nancy,Institut Lorrain du Coeur et des Vaisseaux, FCRIN INI-CRCT, Nancy, France.
  • Mariottoni B; Department of Cardiology, Cortona Hospital, Arezzo, Italy.
  • Brunner-La Rocca HP; Department of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Ahmed FZ; Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.
  • Verdonschot J; Department of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Collier T; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Cuthbert JJ; Department of Academic Cardiology, Castle Hill Hospital, Hull York Medical School (at University of Hull), Kingston upon Hull, UK.
  • Petutschnigg J; Department of Cardiology, Charité Universitätsmedizin Berlin, Berlin, Germany.
  • Mujaj B; DZHK (German Center of Cardiovascular Research), Partner Site Berlin, Berlin, Germany.
  • Girerd N; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
  • González A; Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique, INSERM 1433, CHRU de Nancy,Institut Lorrain du Coeur et des Vaisseaux, FCRIN INI-CRCT, Nancy, France.
  • Clark AL; Program of Cardiovascular Diseases, CIMA Universidad de Navarra and IdiSNA, Pamplona, Spain.
  • Cosmi F; CIBERCV, Carlos III Institute of Health, Madrid, Spain.
  • Staessen JA; Department of Academic Cardiology, Castle Hill Hospital, Hull York Medical School (at University of Hull), Kingston upon Hull, UK.
  • Heymans S; Department of Cardiology, Cortona Hospital, Arezzo, Italy.
  • Latini R; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
  • Rossignol P; Department of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Zannad F; Department of Cardiovascular Sciences, Centre for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium.
  • Cleland JGF; The Netherlands Heart Institute, Utrecht, The Netherlands.
Eur J Heart Fail ; 22(9): 1711-1723, 2020 09.
Article en En | MEDLINE | ID: mdl-31950604
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Eur J Heart Fail Asunto de la revista: CARDIOLOGIA Año: 2020 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Eur J Heart Fail Asunto de la revista: CARDIOLOGIA Año: 2020 Tipo del documento: Article