HIV infection confers distinct mechanisms in severe drug eruption: Endogenous virus activation with aberrant Th2/Th1 and CD8<sup>+</sup> T cells function.

Tang, Jun-Ting; Li, Yu-Ye; Zhang, Yi; Liu, Jun; Guan, Wei; Wang, Rui-Rui; He, Li-Ping; Zhang, Jian-Bo; Kuang, Yi-Qun

HIV infection confers distinct mechanisms in severe drug eruption: Endogenous virus activation with aberrant Th2/Th1 and CD8⁺ T cells function.

Tang, Jun-Ting; Li, Yu-Ye; Zhang, Yi; Liu, Jun; Guan, Wei; Wang, Rui-Rui; He, Li-Ping; Zhang, Jian-Bo; Kuang, Yi-Qun.

Afiliación

Tang JT; Department of Dermatology and Venerology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
Li YY; Department of Dermatology and Venerology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zhang Y; Department of Chinese Medicine, Yunnan University of Chinese Medicine, Kunming, China.
Liu J; Department of HIV/AIDS, Third People's Hospital of Kunming, Kunming, China.
Guan W; Department of HIV/AIDS, Third People's Hospital of Kunming, Kunming, China.
Wang RR; Department of Chinese Medicine, Yunnan University of Chinese Medicine, Kunming, China.
He LP; School of Public Health, Kunming Medical University, Kunming, China.
Zhang JB; Department of Dermatology and Venerology, Second People's Hospital of Dali, Dali, China.
Kuang YQ; NHC Key Laboratory of Drug Addiction Medicine, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, China.

Clin Exp Pharmacol Physiol ; 47(6): 1005-1013, 2020 06.

Article en En | MEDLINE | ID: mdl-31991490

Asunto(s)

Linfocitos T CD8-positivos/virología; Citomegalovirus/patogenicidad; Erupciones por Medicamentos/virología; Infecciones por VIH/virología; Herpesvirus Humano 4/patogenicidad; Células TH1/virología; Células Th2/virología; Activación Viral; Adulto; Linfocitos T CD8-positivos/inmunología; Linfocitos T CD8-positivos/metabolismo; Estudios de Casos y Controles; Citocinas/sangre; Citomegalovirus/inmunología; Erupciones por Medicamentos/sangre; Erupciones por Medicamentos/inmunología; Femenino; VIH/inmunología; VIH/patogenicidad; Infecciones por VIH/sangre; Infecciones por VIH/inmunología; Herpesvirus Humano 4/inmunología; Interacciones Huésped-Patógeno; Humanos; Huésped Inmunocomprometido; Mediadores de Inflamación/sangre; Masculino; Persona de Mediana Edad; Fenotipo; Índice de Severidad de la Enfermedad; Células TH1/inmunología; Células TH1/metabolismo; Células Th2/inmunología; Células Th2/metabolismo

Palabras clave

T lymphocytes; acquired immune deficiency syndrome; drug eruption; human immunodeficiency virus; inflammatory cytokines

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Activación Viral / Infecciones por VIH / Erupciones por Medicamentos / Herpesvirus Humano 4 / Células Th2 / Células TH1 / Linfocitos T CD8-positivos / Citomegalovirus Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Clin Exp Pharmacol Physiol Año: 2020 Tipo del documento: Article

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