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Ablation of the N terminus of cardiac essential light chain promotes the super-relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice.
Sitbon, Yoel H; Kazmierczak, Katarzyna; Liang, Jingsheng; Yadav, Sunil; Veerasammy, Melanie; Kanashiro-Takeuchi, Rosemeire M; Szczesna-Cordary, Danuta.
Afiliación
  • Sitbon YH; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
  • Kazmierczak K; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
  • Liang J; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
  • Yadav S; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
  • Veerasammy M; University of Miami, Coral Gables, FL, USA.
  • Kanashiro-Takeuchi RM; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
  • Szczesna-Cordary D; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL, USA.
FEBS J ; 287(18): 3989-4004, 2020 09.
Article en En | MEDLINE | ID: mdl-32034976
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cadenas Ligeras de Miosina / Mutación / Contracción Miocárdica Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cadenas Ligeras de Miosina / Mutación / Contracción Miocárdica Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article