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MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.
Venkatesh, Divya; O'Brien, Nicholas A; Zandkarimi, Fereshteh; Tong, David R; Stokes, Michael E; Dunn, Denise E; Kengmana, Everett S; Aron, Allegra T; Klein, Alyssa M; Csuka, Joleen M; Moon, Sung-Hwan; Conrad, Marcus; Chang, Christopher J; Lo, Donald C; D'Alessandro, Angelo; Prives, Carol; Stockwell, Brent R.
Afiliación
  • Venkatesh D; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • O'Brien NA; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Zandkarimi F; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Tong DR; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Stokes ME; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Dunn DE; Center for Drug Discovery, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Kengmana ES; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Aron AT; Department of Chemistry, University of California at Berkeley, Berkeley, California 94720, USA.
  • Klein AM; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, New York 10032, USA.
  • Csuka JM; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Moon SH; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Conrad M; Helmholtz Zentrum München, Institute of Metabolism and Cell Death, Neuherberg 85764, Germany.
  • Chang CJ; Department of Chemistry, University of California at Berkeley, Berkeley, California 94720, USA.
  • Lo DC; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
  • D'Alessandro A; Center for Drug Discovery, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Prives C; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado 80045, USA.
  • Stockwell BR; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
Genes Dev ; 34(7-8): 526-543, 2020 04 01.
Article en En | MEDLINE | ID: mdl-32079652
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas de Ciclo Celular / PPAR alfa / Proteínas Proto-Oncogénicas c-mdm2 / Metabolismo de los Lípidos / Ferroptosis Tipo de estudio: Prognostic_studies Idioma: En Revista: Genes Dev Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas de Ciclo Celular / PPAR alfa / Proteínas Proto-Oncogénicas c-mdm2 / Metabolismo de los Lípidos / Ferroptosis Tipo de estudio: Prognostic_studies Idioma: En Revista: Genes Dev Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article