Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.

Shi, Shujie; Montalbetti, Nicolas; Wang, Xueqi; Rush, Brittney M; Marciszyn, Allison L; Baty, Catherine J; Tan, Roderick J; Carattino, Marcelo D; Kleyman, Thomas R

Shi, Shujie; Montalbetti, Nicolas; Wang, Xueqi; Rush, Brittney M; Marciszyn, Allison L; Baty, Catherine J; Tan, Roderick J; Carattino, Marcelo D; Kleyman, Thomas R.

Afiliación

Shi S; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 shs117@pitt.edu.
Montalbetti N; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Wang X; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Rush BM; Department of Nephrology, Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China.
Marciszyn AL; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Baty CJ; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Tan RJ; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Carattino MD; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Kleyman TR; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.

J Biol Chem ; 295(15): 4950-4962, 2020 04 10.

Article en En | MEDLINE | ID: mdl-32079677

Asunto(s)

Arildialquilfosfatasa/metabolismo; Membrana Celular/metabolismo; Canales Epiteliales de Sodio/metabolismo; Oocitos/metabolismo; Sodio/metabolismo; Glándula Tiroides/metabolismo; Animales; Arildialquilfosfatasa/genética; Canales Epiteliales de Sodio/genética; Transporte Iónico; Ratones; Chaperonas Moleculares; Oocitos/citología; Ratas; Transducción de Señal; Glándula Tiroides/citología; Xenopus laevis

Palabras clave

MEC-6; PON3; aldosterone; chaperone; degenerin; epithelial sodium channel (ENaC); hypertension; kidney

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Oocitos / Sodio / Glándula Tiroides / Membrana Celular / Arildialquilfosfatasa / Canales Epiteliales de Sodio Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article

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