Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.

Shubin, Nicholas J; Clauson, Morgan; Niino, Kerri; Kasprzak, Victoria; Tsuha, Avery; Guga, Eric; Bhise, Gauri; Acharya, Manasa; Snyder, Jessica M; Debley, Jason S; Ziegler, Steven F; Piliponsky, Adrian M

Shubin, Nicholas J; Clauson, Morgan; Niino, Kerri; Kasprzak, Victoria; Tsuha, Avery; Guga, Eric; Bhise, Gauri; Acharya, Manasa; Snyder, Jessica M; Debley, Jason S; Ziegler, Steven F; Piliponsky, Adrian M.

Afiliación

Shubin NJ; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Clauson M; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Niino K; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Kasprzak V; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Tsuha A; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Guga E; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Bhise G; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Acharya M; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Snyder JM; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, 98195, USA.
Debley JS; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 98101, USA.
Ziegler SF; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, WA, 98105, USA.
Piliponsky AM; Immunology Program, Benaroya Research Institute at Virginia Mason, Seattle, WA, 98101, USA.

Mucosal Immunol ; 13(4): 584-594, 2020 07.

Article en En | MEDLINE | ID: mdl-32103153

Asunto(s)

Apoptosis/efectos de los fármacos; Caspasa 1/metabolismo; Citocinas/farmacología; Sustancias Protectoras/farmacología; Mucosa Respiratoria/efectos de los fármacos; Mucosa Respiratoria/metabolismo; Animales; Apoptosis/genética; Biomarcadores; Bleomicina/efectos adversos; Caspasa 3/metabolismo; Modelos Animales de Enfermedad; Susceptibilidad a Enfermedades; Células Epiteliales/efectos de los fármacos; Células Epiteliales/metabolismo; Humanos; Inmunoglobulinas/metabolismo; Inmunohistoquímica; Inflamación/tratamiento farmacológico; Inflamación/etiología; Inflamación/metabolismo; Ratones; Ratones Noqueados; Unión Proteica; Receptores de Citocinas/metabolismo; Mucosa Respiratoria/patología; Enfermedades Respiratorias/tratamiento farmacológico; Enfermedades Respiratorias/etiología; Enfermedades Respiratorias/metabolismo; Transducción de Señal/efectos de los fármacos; Subgrupos de Linfocitos T/inmunología; Subgrupos de Linfocitos T/metabolismo; Proteína bcl-X/genética; Proteína bcl-X/metabolismo; Linfopoyetina del Estroma Tímico

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Citocinas / Apoptosis / Sustancias Protectoras / Caspasa 1 / Mucosa Respiratoria Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Mucosal Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article

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