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Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
Cribbs, Adam P; Terlecki-Zaniewicz, Stefan; Philpott, Martin; Baardman, Jeroen; Ahern, David; Lindow, Morten; Obad, Susanna; Oerum, Henrik; Sampey, Brante; Mander, Palwinder K; Penn, Henry; Wordsworth, Paul; Bowness, Paul; de Winther, Menno; Prinjha, Rab K; Feldmann, Marc; Oppermann, Udo.
Afiliación
  • Cribbs AP; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom; adam.cribbs@imm.ox.ac.uk marc.feldmann@kennedy.ox.ac.uk udo.oppermann@s
  • Terlecki-Zaniewicz S; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom.
  • Philpott M; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom.
  • Baardman J; Experimental Vascular Biology, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
  • Ahern D; Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7FY Oxford, United Kingdom.
  • Lindow M; Roche Innovation Center Copenhagen A/S, DK 2970 Hørsholm, Denmark.
  • Obad S; Roche Innovation Center Copenhagen A/S, DK 2970 Hørsholm, Denmark.
  • Oerum H; Roche Innovation Center Copenhagen A/S, DK 2970 Hørsholm, Denmark.
  • Sampey B; Metabolon Inc., Durham, NC 27713.
  • Mander PK; Epinova Discovery Performance Unit, Medicines Research Centre, GlaxoSmithKline R&D, SG1 2NY Stevenage, United Kingdom.
  • Penn H; Arthritis Centre, Northwick Park Hospital, HA13UJ Harrow, United Kingdom.
  • Wordsworth P; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom.
  • Bowness P; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom.
  • de Winther M; Institute for Cardiovascular Prevention, Ludwig Maximilians University, 80336 Munich, Germany.
  • Prinjha RK; Epinova Discovery Performance Unit, Medicines Research Centre, GlaxoSmithKline R&D, SG1 2NY Stevenage, United Kingdom.
  • Feldmann M; Botnar Research Center, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7LD Oxford, United Kingdom; adam.cribbs@imm.ox.ac.uk marc.feldmann@kennedy.ox.ac.uk udo.oppermann@s
  • Oppermann U; Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Unit, University of Oxford, OX3 7FY Oxford, United Kingdom.
Proc Natl Acad Sci U S A ; 117(11): 6056-6066, 2020 03 17.
Article en En | MEDLINE | ID: mdl-32123118
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Benzazepinas / Histonas / Histona Demetilasas / Histona Demetilasas con Dominio de Jumonji / Células Th17 Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Benzazepinas / Histonas / Histona Demetilasas / Histona Demetilasas con Dominio de Jumonji / Células Th17 Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article