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Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.
Eskiocak, Ugur; Guzman, Wilson; Wolf, Benjamin; Cummings, Christine; Milling, Lauren; Wu, Hsin-Jung; Ophir, Michael; Lambden, Conner; Bakhru, Pearl; Gilmore, Dana C; Ottinger, Samantha; Liu, Lucy; McConaughy, William K; He, Sunny Q; Wang, Chao; Leung, Cheuk Lun; Lajoie, Jason; Carson, William F; Zizlsperger, Nora; Schmidt, Michael M; Anderson, Ana C; Bobrowicz, Piotr; Schuetz, Thomas J; Tighe, Robert.
Afiliación
  • Eskiocak U; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Guzman W; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Wolf B; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Cummings C; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Milling L; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Wu HJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.
  • Ophir M; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Lambden C; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Bakhru P; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Gilmore DC; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Ottinger S; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Liu L; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • McConaughy WK; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • He SQ; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Wang C; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Leung CL; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Lajoie J; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Carson WF; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Zizlsperger N; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Schmidt MM; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Anderson AC; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Bobrowicz P; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Schuetz TJ; Compass Therapeutics, Cambridge, Massachusetts, USA.
  • Tighe R; Compass Therapeutics, Cambridge, Massachusetts, USA.
JCI Insight ; 5(5)2020 03 12.
Article en En | MEDLINE | ID: mdl-32161196
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Miembro 9 de la Superfamilia de Receptores de Factores de Necrosis Tumoral / Inmunoterapia / Anticuerpos Monoclonales / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: JCI Insight Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Miembro 9 de la Superfamilia de Receptores de Factores de Necrosis Tumoral / Inmunoterapia / Anticuerpos Monoclonales / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: JCI Insight Año: 2020 Tipo del documento: Article