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Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability.
Gitlin-Domagalska, Agata; Debowski, Dawid; Gucwa, Katarzyna; Starego, Dominika; Ptaszynska, Natalia; Sieradzan, Adam; Karczynska, Agnieszka; Samsonov, Sergey A; Mangold, Martin; Gütschow, Michael; Legowska, Anna; Rolka, Krzysztof.
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  • Gitlin-Domagalska A; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Debowski D; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland. Electronic address: dawid.debowski@ug.edu.pl.
  • Gucwa K; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Starego D; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Ptaszynska N; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Sieradzan A; Faculty of Chemistry, Department of Theoretical Chemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Karczynska A; Faculty of Chemistry, Department of Theoretical Chemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Samsonov SA; Faculty of Chemistry, Department of Theoretical Chemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Mangold M; Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.
  • Gütschow M; Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.
  • Legowska A; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
  • Rolka K; Faculty of Chemistry, Department of Molecular Biochemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland.
Biochimie ; 171-172: 178-186, 2020.
Article en En | MEDLINE | ID: mdl-32169666
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Péptidos / Serina Endopeptidasas Idioma: En Revista: Biochimie Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Péptidos / Serina Endopeptidasas Idioma: En Revista: Biochimie Año: 2020 Tipo del documento: Article