HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response.

Katiyar, Arpit; Fujimoto, Mitsuaki; Tan, Ke; Kurashima, Ai; Srivastava, Pratibha; Okada, Mariko; Takii, Ryosuke; Nakai, Akira

Katiyar, Arpit; Fujimoto, Mitsuaki; Tan, Ke; Kurashima, Ai; Srivastava, Pratibha; Okada, Mariko; Takii, Ryosuke; Nakai, Akira.

Afiliación

Katiyar A; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Fujimoto M; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Tan K; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Kurashima A; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Srivastava P; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Okada M; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Takii R; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.
Nakai A; Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.

FEBS Open Bio ; 10(6): 1135-1148, 2020 06.

Article en En | MEDLINE | ID: mdl-32302062

Asunto(s)

Factores de Transcripción del Choque Térmico/metabolismo; Mitocondrias/metabolismo; Chaperonas Moleculares/genética; Respuesta de Proteína Desplegada/genética; Animales; Proteínas de Unión al ADN/genética; Proteínas de Unión al ADN/metabolismo; Fibroblastos; Técnicas de Silenciamiento del Gen; Células HEK293; Células HeLa; Factores de Transcripción del Choque Térmico/genética; Humanos; Potencial de la Membrana Mitocondrial/genética; Ratones; Proteínas Mitocondriales/genética; Proteínas Mitocondriales/metabolismo; Fosforilación; Regiones Promotoras Genéticas/genética; Interferencia de ARN; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo

Palabras clave

HSF1; SSBP1; heat shock protein; mitochondria; proteostasis; proteotoxic stress

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Chaperonas Moleculares / Respuesta de Proteína Desplegada / Factores de Transcripción del Choque Térmico / Mitocondrias Idioma: En Revista: FEBS Open Bio Año: 2020 Tipo del documento: Article

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