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Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition.
Mondal, Gourish; Lee, Julieann C; Ravindranathan, Ajay; Villanueva-Meyer, Javier E; Tran, Quynh T; Allen, Sariah J; Barreto, Jairo; Gupta, Rohit; Doo, Pamela; Van Ziffle, Jessica; Onodera, Courtney; Devine, Patrick; Grenert, James P; Samuel, David; Li, Rong; Metrock, Laura K; Jin, Lee-Way; Antony, Reuben; Alashari, Mouied; Cheshier, Samuel; Whipple, Nicholas S; Bruggers, Carol; Raffel, Corey; Gupta, Nalin; Kline, Cassie N; Reddy, Alyssa; Banerjee, Anu; Hall, Matthew D; Mehta, Minesh P; Khatib, Ziad; Maher, Ossama M; Brathwaite, Carole; Pekmezci, Melike; Phillips, Joanna J; Bollen, Andrew W; Tihan, Tarik; Lucas, John T; Broniscer, Alberto; Berger, Mitchel S; Perry, Arie; Orr, Brent A; Solomon, David A.
Afiliación
  • Mondal G; Department of Pathology, University of California, San Francisco, CA, USA.
  • Lee JC; Department of Pathology, University of California, San Francisco, CA, USA.
  • Ravindranathan A; Department of Pathology, University of California, San Francisco, CA, USA.
  • Villanueva-Meyer JE; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
  • Tran QT; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Allen SJ; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Barreto J; Department of Pathology, University of California, San Francisco, CA, USA.
  • Gupta R; Department of Pathology, University of California, San Francisco, CA, USA.
  • Doo P; Institute for Human Genetics, University of California, San Francisco, CA, USA.
  • Van Ziffle J; Department of Pathology, University of California, San Francisco, CA, USA.
  • Onodera C; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Devine P; Department of Pathology, University of California, San Francisco, CA, USA.
  • Grenert JP; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Samuel D; Department of Pathology, University of California, San Francisco, CA, USA.
  • Li R; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Metrock LK; Department of Pathology, University of California, San Francisco, CA, USA.
  • Jin LW; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Antony R; Department of Hematology/Oncology, Valley Children's Hospital, Madera, CA, USA.
  • Alashari M; Department of Pathology, Children's of Alabama, Birmingham, AL, USA.
  • Cheshier S; Department of Pediatric Hematology/Oncology, University of Alabama, Birmingham, AL, USA.
  • Whipple NS; Department of Pathology, University of California Davis Medical Center, Sacramento, CA, USA.
  • Bruggers C; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA, USA.
  • Raffel C; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Gupta N; Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Kline CN; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Reddy A; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Banerjee A; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
  • Hall MD; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
  • Mehta MP; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.
  • Khatib Z; Department of Neurology, University of California, San Francisco, CA, USA.
  • Maher OM; Department of Neurology, University of California, San Francisco, CA, USA.
  • Brathwaite C; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.
  • Pekmezci M; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.
  • Phillips JJ; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.
  • Bollen AW; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA.
  • Tihan T; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA.
  • Lucas JT; Department of Pathology, Nicklaus Children's Hospital, Miami, FL, USA.
  • Broniscer A; Department of Pathology, University of California, San Francisco, CA, USA.
  • Berger MS; Department of Pathology, University of California, San Francisco, CA, USA.
  • Perry A; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
  • Orr BA; Department of Pathology, University of California, San Francisco, CA, USA.
  • Solomon DA; Department of Pathology, University of California, San Francisco, CA, USA.
Acta Neuropathol ; 139(6): 1071-1088, 2020 06.
Article en En | MEDLINE | ID: mdl-32303840
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Glioma / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Glioma / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article