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Comparison of the Antioxidant Activities and Phenolic Content of Five Lonicera Flowers by HPLC-DAD/MS-DPPH and Chemometrics.
Zhou, Rong-Rong; Liu, Xue-Hui; Chen, Lin; Huang, Jian-Hua; Liang, Xue-Juan; Wan, Dan; Zhang, Shui-Han; Huang, Lu-Qi.
Afiliación
  • Zhou RR; Changchun University of Chinese Medicine, College of Pharmacy, Changchun, China.
  • Liu XH; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Chen L; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Huang JH; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Liang XJ; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Wan D; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Zhang SH; Hunan Academy of Chinese Medicine, Research Institute of Chinese Medicine, Changsha, China.
  • Huang LQ; Changchun University of Chinese Medicine, College of Pharmacy, Changchun, China.
Int J Anal Chem ; 2020: 2348903, 2020.
Article en En | MEDLINE | ID: mdl-32308684
ABSTRACT
The Lonicera plants (family Caprifoliaceae) with strong antioxidant activity are used as potential health-supporting phytochemicals. Studying the detailed relationships between bioactive compounds and their antioxidant activity is important for further comprehensive development and application of them. In this paper, the antioxidant capacities and compositions of five species of Lonicera flowers were investigated by using the online HPLC-DAD/MS-DPPH method. Results indicated that the samples contained higher amounts of phenols had better antioxidant activity. Furthermore, principal component analysis and linear regression were further used to analyze the correlations between antioxidant capacity and compounds and find the compounds having higher contribution to antioxidant activity. 5-O-Caffeoylquinic acid, 4-O-caffeoylshikimic acid, methyl-5-O-caffeoylquinate, 1,4-di-O-caffeoylquinic acid, and 3,4,5-tri-O-caffeoylquinic acid were screened as stronger antioxidant candidates. In this study, HPLC-DAD/MS and antioxidant activity methods were combined together to analyze the compounds' information and activity assays of Lonicera, which might provide more evidence for its quality control.

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Int J Anal Chem Año: 2020 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Int J Anal Chem Año: 2020 Tipo del documento: Article