Fibroblast rejuvenation by mechanical reprogramming and redifferentiation.

Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim; Bharti, Aradhana; Mitra, Aninda; Shivashankar, G V

Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim; Bharti, Aradhana; Mitra, Aninda; Shivashankar, G V.

Afiliación

Roy B; Mechanobiology Institute, National University of Singapore, 117411 Singapore.
Yuan L; Institute of Molecular Oncology, Italian Foundation for Cancer Research, 20139 Milan, Italy.
Lee Y; Division of Biology and Chemistry, Paul Scherrer Institut, 5232 Villigen, Switzerland.
Bharti A; Mechanobiology Institute, National University of Singapore, 117411 Singapore.
Mitra A; Mechanobiology Institute, National University of Singapore, 117411 Singapore.
Shivashankar GV; Mechanobiology Institute, National University of Singapore, 117411 Singapore.

Proc Natl Acad Sci U S A ; 117(19): 10131-10141, 2020 05 12.

Article en En | MEDLINE | ID: mdl-32350144

Asunto(s)

Diferenciación Celular; Reprogramación Celular; Fibroblastos/citología; Medicina Regenerativa; Rejuvenecimiento/fisiología; Anciano; Animales; Proliferación Celular; Células Cultivadas; Colágeno Tipo I/metabolismo; Matriz Extracelular/metabolismo; Fibroblastos/metabolismo; Fibronectinas/metabolismo; Humanos; Laminina/metabolismo; Ratones; Células 3T3 NIH; Esferoides Celulares/citología; Esferoides Celulares/metabolismo

Palabras clave

engineered 3D tissue; lateral confinement; redifferentiation; rejuvenation; stem-cell-like state

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rejuvenecimiento / Diferenciación Celular / Medicina Regenerativa / Reprogramación Celular / Fibroblastos Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google