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Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial.
Hung, Ivan Fan-Ngai; Lung, Kwok-Cheung; Tso, Eugene Yuk-Keung; Liu, Raymond; Chung, Tom Wai-Hin; Chu, Man-Yee; Ng, Yuk-Yung; Lo, Jenny; Chan, Jacky; Tam, Anthony Raymond; Shum, Hoi-Ping; Chan, Veronica; Wu, Alan Ka-Lun; Sin, Kit-Man; Leung, Wai-Shing; Law, Wai-Lam; Lung, David Christopher; Sin, Simon; Yeung, Pauline; Yip, Cyril Chik-Yan; Zhang, Ricky Ruiqi; Fung, Agnes Yim-Fong; Yan, Erica Yuen-Wing; Leung, Kit-Hang; Ip, Jonathan Daniel; Chu, Allen Wing-Ho; Chan, Wan-Mui; Ng, Anthony Chin-Ki; Lee, Rodney; Fung, Kitty; Yeung, Alwin; Wu, Tak-Chiu; Chan, Johnny Wai-Man; Yan, Wing-Wah; Chan, Wai-Ming; Chan, Jasper Fuk-Woo; Lie, Albert Kwok-Wai; Tsang, Owen Tak-Yin; Cheng, Vincent Chi-Chung; Que, Tak-Lun; Lau, Chak-Sing; Chan, Kwok-Hung; To, Kelvin Kai-Wang; Yuen, Kwok-Yung.
Afiliación
  • Hung IF; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Lung KC; Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
  • Tso EY; Department of Medicine, United Christian Hospital, Hong Kong SAR, China.
  • Liu R; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong SAR, China.
  • Chung TW; Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Chu MY; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.
  • Ng YY; Department of Medicine, Tuen Mun Hospital, Hong Kong SAR, China.
  • Lo J; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong SAR, China.
  • Chan J; Department of Medicine, Princess Margaret Hospital, Hong Kong SAR, China.
  • Tam AR; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Shum HP; Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
  • Chan V; Department of Medicine, United Christian Hospital, Hong Kong SAR, China.
  • Wu AK; Department of Microbiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
  • Sin KM; Department of Medicine, Tuen Mun Hospital, Hong Kong SAR, China.
  • Leung WS; Department of Medicine, Princess Margaret Hospital, Hong Kong SAR, China.
  • Law WL; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.
  • Lung DC; Department of Microbiology, Queen Elizabeth Hospital, Hong Kong SAR, China.
  • Sin S; Department of Intensive Care, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Yeung P; Department of Intensive Care, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Yip CC; Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Zhang RR; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Fung AY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Yan EY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Leung KH; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Ip JD; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Chu AW; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Chan WM; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Ng AC; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Lee R; Department of Microbiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
  • Fung K; Department of Microbiology, United Christian Hospital, Hong Kong SAR, China.
  • Yeung A; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong SAR, China.
  • Wu TC; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.
  • Chan JW; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.
  • Yan WW; Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
  • Chan WM; Department of Intensive Care, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Chan JF; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Lie AK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Tsang OT; Department of Medicine, Princess Margaret Hospital, Hong Kong SAR, China.
  • Cheng VC; Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Que TL; Department of Microbiology, Tuen Mun Hospital, Hong Kong SAR, China.
  • Lau CS; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Chan KH; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • To KK; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China.
  • Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China. Electronic address: kyyuen@hku.hk.
Lancet ; 395(10238): 1695-1704, 2020 05 30.
Article en En | MEDLINE | ID: mdl-32401715
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Ribavirina / Infecciones por Coronavirus / Ritonavir / Lopinavir / Interferon beta-1b Tipo de estudio: Clinical_trials País/Región como asunto: Asia Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Ribavirina / Infecciones por Coronavirus / Ritonavir / Lopinavir / Interferon beta-1b Tipo de estudio: Clinical_trials País/Región como asunto: Asia Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article