Beta-band power modulation in the human hippocampus during a reaching task.
J Neural Eng
; 17(3): 036022, 2020 06 12.
Article
en En
| MEDLINE
| ID: mdl-32413878
ABSTRACT
OBJECTIVE:
Characterize the role of the beta-band (13-30 Hz) in the human hippocampus during the execution of voluntary movement.APPROACH:
We recorded electrophysiological activity in human hippocampus during a reach task using stereotactic electroencephalography (SEEG). SEEG has previously been utilized to study the theta band (3-8 Hz) in conflict processing and spatial navigation, but most studies of hippocampal activity during movement have used noninvasive measures such as fMRI. We analyzed modulation in the beta band (13-30 Hz), which is known to play a prominent role throughout the motor system including the cerebral cortex and basal ganglia. We conducted the classic 'center-out' direct-reach experiment with nine patients undergoing surgical treatment for medically refractory epilepsy. MAINRESULTS:
In seven of the nine patients, power spectral analysis showed a statistically significant decrease in power within the beta band (13-30 Hz) during the response phase, compared to the fixation phase, of the center-out direct-reach task using the Wilcoxon signed-rank hypothesis test (p < 0.05).SIGNIFICANCE:
This finding is consistent with previous literature suggesting that the hippocampus may be involved in the execution of movement, and it is the first time that changes in beta-band power have been demonstrated in the hippocampus using human electrophysiology. Our findings suggest that beta-band modulation in the human hippocampus may play a role in the execution of voluntary movement.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ritmo beta
/
Movimiento
Idioma:
En
Revista:
J Neural Eng
Asunto de la revista:
NEUROLOGIA
Año:
2020
Tipo del documento:
Article