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Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.
Pérez, María José; Ivanyuk, Dina; Panagiotakopoulou, Vasiliki; Di Napoli, Gabriele; Kalb, Stefanie; Brunetti, Dario; Al-Shaana, Rawaa; Kaeser, Stephan A; Fraschka, Sabine Anne-Kristin; Jucker, Mathias; Zeviani, Massimo; Viscomi, Carlo; Deleidi, Michela.
Afiliación
  • Pérez MJ; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Ivanyuk D; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Panagiotakopoulou V; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Di Napoli G; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Kalb S; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Brunetti D; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Al-Shaana R; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Kaeser SA; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Fraschka SA; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Jucker M; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Zeviani M; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Viscomi C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Deleidi M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Mol Psychiatry ; 26(10): 5733-5750, 2021 10.
Article en En | MEDLINE | ID: mdl-32632204
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Enfermedad de Alzheimer Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Enfermedad de Alzheimer Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2021 Tipo del documento: Article