TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.

Monlish, Darlene A; Greenberg, Zev J; Bhatt, Sima T; Leonard, Kathryn M; Romine, Molly P; Dong, Qian; Bendesky, Lauren; Duncavage, Eric J; Magee, Jeffrey A; Schuettpelz, Laura G

Monlish, Darlene A; Greenberg, Zev J; Bhatt, Sima T; Leonard, Kathryn M; Romine, Molly P; Dong, Qian; Bendesky, Lauren; Duncavage, Eric J; Magee, Jeffrey A; Schuettpelz, Laura G.

Afiliación

Monlish DA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Greenberg ZJ; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Bhatt ST; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Leonard KM; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Romine MP; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Dong Q; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Bendesky L; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Duncavage EJ; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
Magee JA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Schuettpelz LG; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. Electronic address: Schuettpelz_l@wustl.edu.

Exp Hematol ; 88: 42-55, 2020 08.

Article en En | MEDLINE | ID: mdl-32652111

Asunto(s)

Células Madre Hematopoyéticas/metabolismo; Proteínas de Homeodominio/metabolismo; Síndromes Mielodisplásicos/metabolismo; Proteínas de Complejo Poro Nuclear/metabolismo; Transducción de Señal; Receptor Toll-Like 2/metabolismo; Receptor Toll-Like 6/metabolismo; Factores de Transcripción/metabolismo; Animales; Modelos Animales de Enfermedad; Células Madre Hematopoyéticas/patología; Proteínas de Homeodominio/genética; Ratones; Ratones Noqueados; Síndromes Mielodisplásicos/genética; Síndromes Mielodisplásicos/patología; Proteínas de Complejo Poro Nuclear/genética; Receptor Toll-Like 2/genética; Receptor Toll-Like 6/genética; Factores de Transcripción/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Síndromes Mielodisplásicos / Células Madre Hematopoyéticas / Transducción de Señal / Proteínas de Homeodominio / Proteínas de Complejo Poro Nuclear / Receptor Toll-Like 2 / Receptor Toll-Like 6 Tipo de estudio: Prognostic_studies Idioma: En Revista: Exp Hematol Año: 2020 Tipo del documento: Article

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