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Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Zhang, Siwei; Zhang, Hanwen; Zhou, Yifan; Qiao, Min; Zhao, Siming; Kozlova, Alena; Shi, Jianxin; Sanders, Alan R; Wang, Gao; Luo, Kaixuan; Sengupta, Subhajit; West, Siobhan; Qian, Sheng; Streit, Michael; Avramopoulos, Dimitrios; Cowan, Chad A; Chen, Mengjie; Pang, Zhiping P; Gejman, Pablo V; He, Xin; Duan, Jubao.
Afiliación
  • Zhang S; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Zhang H; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Zhou Y; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Qiao M; The Graduate Program in Biophysical Sciences, University of Chicago, Chicago, IL 60637, USA.
  • Zhao S; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Kozlova A; Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Shi J; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Sanders AR; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Wang G; Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
  • Luo K; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Sengupta S; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA.
  • West S; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Qian S; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Streit M; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Avramopoulos D; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Cowan CA; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
  • Chen M; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
  • Pang ZP; Department of Genetic Medicine and Psychiatry, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Gejman PV; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.
  • He X; Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
  • Duan J; Department of Neuroscience and Cell Biology, Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Science ; 369(6503): 561-565, 2020 07 31.
Article en En | MEDLINE | ID: mdl-32732423
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Esquizofrenia / Encéfalo / Cromatina / Alelos / Células Madre Pluripotentes Inducidas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Science Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Esquizofrenia / Encéfalo / Cromatina / Alelos / Células Madre Pluripotentes Inducidas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Science Año: 2020 Tipo del documento: Article