Prognostic value of lung ultrasound in chronic stable ambulatory heart failure patients.
Rev Esp Cardiol (Engl Ed)
; 74(10): 862-869, 2021 Oct.
Article
en En, Es
| MEDLINE
| ID: mdl-32861606
ABSTRACT
INTRODUCTION AND OBJECTIVES:
The role of lung ultrasound (LUS) in acute heart failure (HF) has been widely studied, but little is known about its usefulness in chronic HF. This study assessed the prognostic value of LUS in a cohort of chronic HF stable ambulatory patients.METHODS:
We included consecutive outpatients who attended a scheduled follow-up visit in a HF clinic. LUS was performed in situ. The operators were blinded to clinical data and examined 8 thoracic areas. The sum of B-lines across all lung zones and the quartiles of this addition were used for the analyses. Linear regression and Cox regression analyses were performed. The main clinical outcomes were a composite of all-cause death or hospitalization for HF and mortality from any cause.RESULTS:
A total of 577 individuals were included (72% men; 69± 12 years). The mean number of B-lines was 5±6. During a mean follow-up of 31±7 months, 157 patients experienced the main clinical outcome and 111 died. Having ≥ 8 B-lines (Q4) doubled the risk of experiencing the composite primary event (P <.001) and increased the risk of death from any cause by 2.6-fold (P <.001). On multivariate analysis, the total sum of B-lines remained independent predictive factor of the composite endpoint (HR, 1.04; 95%CI, 1.02-1.06; P=.002) and of all-cause death (HR, 1.04; 95%CI, 1.02-1.07; P=.001), independently of whether or not N-terminal pro-B-type natriuretic peptide (NT-proBNP) was included in the model (P=.01 and P=.008, respectively), with a 3% to 4% increased risk for each 1-line addition.CONCLUSIONS:
LUS identified patients with stable chronic HF at high risk of death or HF hospitalization.Palabras clave
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Base de datos:
MEDLINE
Asunto principal:
Péptido Natriurético Encefálico
/
Insuficiencia Cardíaca
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Idioma:
En
/
Es
Revista:
Rev Esp Cardiol (Engl Ed)
Año:
2021
Tipo del documento:
Article