The structure of myeloid cell-specific TNF inhibitors affects their biological properties.

Vasilenko, Ekaterina A; Gorshkova, Ekaterina N; Astrakhantseva, Irina V; Drutskaya, Marina S; Tillib, Sergei V; Nedospasov, Sergei A; Mokhonov, Vladislav V

Vasilenko, Ekaterina A; Gorshkova, Ekaterina N; Astrakhantseva, Irina V; Drutskaya, Marina S; Tillib, Sergei V; Nedospasov, Sergei A; Mokhonov, Vladislav V.

Afiliación

Vasilenko EA; Lobachevsky State University, Nizhny Novgorod, Russia.
Gorshkova EN; Lobachevsky State University, Nizhny Novgorod, Russia.
Astrakhantseva IV; Lobachevsky State University, Nizhny Novgorod, Russia.
Drutskaya MS; Sirius University of Science and Technology, Sochi, Russia.
Tillib SV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Nedospasov SA; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Mokhonov VV; Sirius University of Science and Technology, Sochi, Russia.

FEBS Lett ; 594(21): 3542-3550, 2020 11.

Article en En | MEDLINE | ID: mdl-32865225

Asunto(s)

Células Mieloides/efectos de los fármacos; Inhibidores del Factor de Necrosis Tumoral/farmacología; Animales; Anticuerpos Biespecíficos/farmacología; Enfermedad Hepática Inducida por Sustancias y Drogas; Galactosamina; Humanos; Lipopolisacáridos; Macrófagos/efectos de los fármacos; Ratones; Tasa de Supervivencia; Factor de Necrosis Tumoral alfa/farmacología

Palabras clave

VHH; anti-TNF therapy; bispecific antibodies; linkers

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Mieloides / Inhibidores del Factor de Necrosis Tumoral Idioma: En Revista: FEBS Lett Año: 2020 Tipo del documento: Article

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