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An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Hanke, Leo; Vidakovics Perez, Laura; Sheward, Daniel J; Das, Hrishikesh; Schulte, Tim; Moliner-Morro, Ainhoa; Corcoran, Martin; Achour, Adnane; Karlsson Hedestam, Gunilla B; Hällberg, B Martin; Murrell, Ben; McInerney, Gerald M.
Afiliación
  • Hanke L; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Vidakovics Perez L; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Sheward DJ; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Das H; Division of Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
  • Schulte T; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
  • Moliner-Morro A; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, and Division of Infectious Diseases, Karolinska University Hospital, Solna, Stockholm, Sweden.
  • Corcoran M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Achour A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Karlsson Hedestam GB; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, and Division of Infectious Diseases, Karolinska University Hospital, Solna, Stockholm, Sweden.
  • Hällberg BM; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Murrell B; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden. martin.hallberg@ki.se.
  • McInerney GM; Karolinska Institutet VR-RÅC, Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany. martin.hallberg@ki.se.
Nat Commun ; 11(1): 4420, 2020 09 04.
Article en En | MEDLINE | ID: mdl-32887876
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Camélidos del Nuevo Mundo / Inhibidores de la Enzima Convertidora de Angiotensina / Infecciones por Coronavirus / Peptidil-Dipeptidasa A / Anticuerpos de Dominio Único / Glicoproteína de la Espiga del Coronavirus / Betacoronavirus Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Camélidos del Nuevo Mundo / Inhibidores de la Enzima Convertidora de Angiotensina / Infecciones por Coronavirus / Peptidil-Dipeptidasa A / Anticuerpos de Dominio Único / Glicoproteína de la Espiga del Coronavirus / Betacoronavirus Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article