SnapShot: ß-Arrestin Functions.

Ahn, Seungkirl; Shenoy, Sudha K; Luttrell, Louis M; Lefkowitz, Robert J

Ahn, Seungkirl; Shenoy, Sudha K; Luttrell, Louis M; Lefkowitz, Robert J.

Afiliación

Ahn S; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Shenoy SK; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Luttrell LM; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Lefkowitz RJ; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA.

Cell ; 182(5): 1362-1362.e1, 2020 09 03.

Article en En | MEDLINE | ID: mdl-32888497

ABSTRACT

ABSTRACT

The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic protein interactions and cellular functions.

Asunto(s)

Arrestinas/metabolismo; Membrana Celular/metabolismo; Mapas de Interacción de Proteínas/fisiología; Receptores Acoplados a Proteínas G/metabolismo; Transducción de Señal/fisiología

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Arrestinas Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Arrestinas Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article