Magnetic resonance imaging criteria of immune checkpoint inhibitor-induced hypophysitis.
Curr Probl Cancer
; 45(1): 100644, 2021 02.
Article
en En
| MEDLINE
| ID: mdl-32888700
ABSTRACT
Autoimmune hypophysitis is a rare complication of immune checkpoint inhibitors. Immune checkpoint inhibitors have been used for advanced stages of melanoma, renal cell carcinoma, and lung cancer. Multiple endocrinopathies, among them hypophysitis, could result as a reverse event from this therapy. MRI is the imaging modality of choice and usually demonstrates pituitary gland hypertrophy, irregular thickening of the pituitary infundibulum, and diffuse enhancement. We present a case of stage IV metastatic renal cell carcinoma complicated with hypophysitis secondary to combined nivolumab and ipilimumab therapy.
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Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Renales
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Hipofisitis
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Ipilimumab
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Nivolumab
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Inhibidores de Puntos de Control Inmunológico
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Neoplasias Renales
Idioma:
En
Revista:
Curr Probl Cancer
Año:
2021
Tipo del documento:
Article