Point-of-Need Diagnostics for Foodborne Pathogen Screening.
SLAS Technol
; 26(1): 55-79, 2021 02.
Article
en En
| MEDLINE
| ID: mdl-33012245
ABSTRACT
Foodborne illness is a major public health issue that results in millions of global infections annually. The burden of such illness sits mostly with developing countries, as access to advanced laboratory equipment and skilled lab technicians, as well as consistent power sources, is limited and expensive. Current gold standards in foodborne pathogen screening involve labor-intensive sample enrichment steps, pathogen isolation and purification, and costly readout machinery. Overall, time to detection can take multiple days, excluding the time it takes to ship samples to off-site laboratories. Efforts have been made to simplify the workflow of such tests by integrating multiple steps of foodborne pathogen screening procedures into a singular device, as well as implementing more point-of-need readout methods. In this review, we explore recent advancements in developing point-of-need devices for foodborne pathogen screening. We discuss the detection of surface markers, nucleic acids, and metabolic products using both paper-based and microfluidic devices, focusing primarily on developments that have been made between 2015 and mid-2020.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ácidos Nucleicos
/
Enfermedades Transmitidas por los Alimentos
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Revista:
SLAS Technol
Año:
2021
Tipo del documento:
Article