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Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer.
Morotti, Matteo; Zois, Christos E; El-Ansari, Rokaya; Craze, Madeleine L; Rakha, Emad A; Fan, Shih-Jung; Valli, Alessandro; Haider, Syed; Goberdhan, Deborah C I; Green, Andrew R; Harris, Adrian L.
Afiliación
  • Morotti M; Hypoxia and Angiogenesis Group, Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, Oxford, OX3 9DS, UK. drmorottimatteo@gmail.com.
  • Zois CE; Hypoxia and Angiogenesis Group, Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, Oxford, OX3 9DS, UK.
  • El-Ansari R; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, NG7 2RD, UK.
  • Craze ML; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, NG7 2RD, UK.
  • Rakha EA; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, NG7 2RD, UK.
  • Fan SJ; Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK.
  • Valli A; Hypoxia and Angiogenesis Group, Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, Oxford, OX3 9DS, UK.
  • Haider S; Hypoxia and Angiogenesis Group, Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, Oxford, OX3 9DS, UK.
  • Goberdhan DCI; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
  • Green AR; Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK.
  • Harris AL; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, NG7 2RD, UK.
Br J Cancer ; 124(2): 494-505, 2021 01.
Article en En | MEDLINE | ID: mdl-33028955
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Estrés Oxidativo / Sistema de Transporte de Aminoácidos A / Neoplasias de la Mama Triple Negativas / Glutamina Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Br J Cancer Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Estrés Oxidativo / Sistema de Transporte de Aminoácidos A / Neoplasias de la Mama Triple Negativas / Glutamina Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Br J Cancer Año: 2021 Tipo del documento: Article