Triazole formation of phosphinyl alkynes with azides through transient protection of phosphine by copper.
Chem Commun (Camb)
; 56(90): 14003-14006, 2020 Nov 12.
Article
en En
| MEDLINE
| ID: mdl-33094760
ABSTRACT
An efficient preparation method of functionalized phosphines by copper-catalyzed azide-alkyne cycloaddition (CuAAC) through the transient protection of phosphine from the Staudinger reaction is disclosed. Diverse phosphines were prepared from phosphinyl alkynes and azides by the click reaction at the ethynyl group without damaging the phosphinyl group. Double- and triple-click assemblies of azides were accomplished by triazole formations and robust azaylide formation.
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Base de datos:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2020
Tipo del documento:
Article